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Which virus is responsible for herpes zoster?

  1. Human Papillomavirus

  2. Varicella zoster virus

  3. Herpes simplex virus

  4. Epstein-Barr virus

The correct answer is: Varicella zoster virus

The virus that is responsible for herpes zoster, also known as shingles, is the Varicella zoster virus. This virus is the same one that causes chickenpox. After a person has had chickenpox, the virus remains dormant in the body and can later reactivate as herpes zoster, typically manifesting as a painful rash or blisters on one side of the body. Understanding the lifecycle of Varicella zoster virus is crucial in recognizing the connection between chickenpox and herpes zoster. The reactivation commonly occurs years after the initial infection, particularly in individuals who are immunocompromised or under significant stress. In contrast, the other viruses listed—such as Human Papillomavirus, Herpes simplex virus, and Epstein-Barr virus—are associated with different infections and conditions. Human Papillomavirus is primarily linked with warts and certain cancers, Herpes simplex virus is commonly known for oral and genital herpes, and Epstein-Barr virus is well-known for causing infectious mononucleosis. Each of these viruses has distinct characteristics and effects on the body, making Varicella zoster virus the sole correct answer for this question.